Program

University of Rochester, Oct 20-23, 2022

THURS OCT 20

18:00 – 21:00 Welcome reception

Location: Flaum Eye Institute

FRI OCT 21

8:30-10:30 Invited session: Vision restoration

Location: SMD Large Auditorium, Rm 2-6424, MC

From prosthetics to optogenetics to gene therapy, new approaches to the technologies and therapies used to restore lost vision have accelerated in the last decade. In this session, experts will provide an overview of the extent to which high-quality vision can be restored based on what we know now, and what might be possible to achieve in the near future.

  • Deep learning-based stimulus optimization for prosthetic vision, Michael Beyeler, University of California, Santa Barbara

  • Restoring vision at the fovea, Juliette McGregor, University of Rochester

  • Genetic therapies for inherited retinal disorders, Rachel Huckfeldt, Massachusetts Eye and Ear

  • The new generation of visual cortical prosthetics, Daniel Yoshor, University of Pennsylvania

10:30-10:40 Break

10:40-11:40 Contributed talks I

Location: SMD Large Auditorium, Rm 2-6424, MC

  • Towards General Video Percepts Cone-by-Cone, Congli Wang, University of California, Berkeley

  • Spectral, Spatial and Temporal Response Properties of Foveal Ganglion Cells, Sara Patterson, University of Rochester

  • Layer-specific, retinotopically-diffuse modulation in human visual cortex by emotional faces, Tong Liu, NIMH

  • Foveal RGCs develop abnormal calcium clearance weeks after photoreceptor ablation, Zhengyang Xu, Institute of Optics, University of Rochester

11:40-13:40 Lunch

13:40–15:40 Invited session: Myopia and myopia control session

Location: Sloan Auditorium (Goergen Hall)

Myopia is an ocular condition where the focal length of the eye’s optics is too short to appropriately focus distant objects and often comes with sequelae of ocular and retinal complications. It is a condition that is on the rise globally and is at epidemic levels, especially in East Asian countries. The goal of this session is to discuss the mechanisms and theories that drive this condition as well as treatments that are being deployed to address myopic development.

  • Interactions between light exposure and diurnal rhythms on the choroid, Lisa Ostrin, University of Houston

  • Early functional changes in the myopic retina compromise emmetropization, Frank Schaeffel, IOB; University of Tübingen

  • Ocular growth regulation and the complexities of optical defocus decoding: A perspective from studies in chicks, Christine F Wildsoet, Herbert Wertheim School of Optometry & Vision Science, UC Berkeley

  • Accommodation during myopia management is related to treatment efficacy, David Troilo, SUNY College of Optometry

15:40-16:20 Break

16:20-17:30 Boynton Award Lecture: Andrew Stockman

Location: Sloan Auditorium (Goergen Hall)

  • Untangling visual processing and sensitivity regulation using data from normals and from patients missing key molecules required for normal visual function, Andrew Stockman, UCL Institute of Ophthalmology

18:00 Poster Session I

Location: Munnerlyn Atrium, Goergen Hall

Dinner provided

SAT OCT 22

Location: Sloan Auditorium (Goergen Hall), unless noted otherwise

8:00-8:30 Breakfast

Location: Goergen Atrium

8:30-10:30 Invited session: Neural network models of the visual system session

Research into network models of visual processing has seen exceptional progress over the past decade, driven largely by advances in machine vision systems based on deep neural networks which now equal or exceed human performance on a variety of tasks. However, the correspondence between machine vision systems and human visual cortex is still unclear and while there appear to be homologies early in the hierarchy, computations and capabilities clearly diverge at later stages. In this session we explore similarities and differences between machine and human visual systems from early visual cortex though to high level representations of objects and semantic information and ask how a constructive dialog between computer science and human neuroscience can benefit both fields.

  • Exploring the function of different forms of visual recurrence with artificial neural networks, Grace Lindsay, New York University

  • Robust information representation in hierarchical networks of the visual cortex, Hannah Choi, Georgia Institute of Technology

  • SueYeon Chung, New York University

  • Reverse-engineering neural code in the language of objects and generative models, Ilker Yildirim, Yale University

10:30-10:45 Break

10:45-11:45 Contributed Talk Session II

  • Detecting subclinical keratoconus by mapping corneal biomechanics using wave-based optical coherence elastography, Fernando Zvietcovich, Daza de Valdes Institute of Optics

  • Ex-vivo human crystalline lenses geometrical changes during simulated disaccommodation, Eduardo Martinez-Enriquez, Instituto de Óptica, Consejo Superior de Investigaciones Cientificas

  • In vivo imaging of immune cell activity in primate retina after photoreceptor ablation, Drew Ashbery, University of Rochester

  • Immune cell speed changes over 5 orders of magnitude in response to inflammation in the retina, Kosha Dholakia, University of Rochester

11:45-12:30 FVM Business Meeting

12:30-14:00 Poster Session II

Lunch provided

14:00-16:00 Invited session: Studies of the visual cortex with sub-millimeter resolution session

Understanding the circuits that process information in early visual cortical areas is essential for the study of vision. This field has benefited from impressive advances in imaging that enable study of single cells and local circuits that mediate feedforward and feedback information in early visual areas. This session will focus on optical and physiological approaches that have enabled insights in the structural and functional architecture of the early visual cortex.

  • Imaging the visual brain at high spatiotemporal resolution, Na Ji, University of California, Berkeley

  • Three-photon imaging reveals the neural basis of fMRI across cortical layers, Prakash Kara, University of Minnesota

  • Eyal Seidemann, UT Austin

  • Sandra J. Kuhlman, Carnegie Mellon University

16:00-16:15 Break

16:15-17:25 2021 Tillyer Award Lecture: David Brainard

  • The Early Visual Encoding: Computations and Consequences, David Brainard, University of Pennsylvania

17:25-17:40 Break

17:40-18:50 2022 Tillyer Award Lecture: Mary Hayhoe

        • Visual Control of Locomotion in Natural Environments, Mary Hayhoe, UT Austin

19:00 start Tillyer and Boynton Award Banquet

Location: Century Club of Rochester, 566 East Ave

SUN OCT 23

Location: Sloan Auditorium (Goergen Hall)

8:00-8:30 Breakfast

8:30-10:30 Invited session: The eye as a window to systemic and neurodegenerative health

The retina can serve as an easily accessible biomarker of vascular and neural health far beyond the eye. This potential is being realized with advances in imaging and analysis approaches, including machine learning. This symposium will explore markers of systemic and neurodegenerative disease revealed in the eye.

  • Disturbances of retinal structure in schizophrenia spectrum disorders and their clinical implications, Steven M. Silverstein, University of Rochester

  • Retinal biomarkers in Alzheimer’s and other brain diseases, Delia Cabrera DeBuc, Bascom Palmer Eye Institute University of Miami

  • Seeking Answers through a keyhole: Harnessing the Synergy of Dynamic OCT/OCT Angiography and Adaptive Optics SLO for Retinal Assessment of Systemic Disease, Richard Rosen, New York Eye and Ear Infirmary of Mount Sinai

  • In vivo study of higher-order retinal hemodynamics in human retinal capillaries, Yuhua Zhang, UC Los Angeles

10:30-10:50 Break

10:50-11:50 Contributed Talk Session III

  • In vivo calcium imaging of macaque foveolar retinal ganglion cells reveals spatiochromatic receptive field properties, Tyler Godat, University of Rochester

  • Identifying Specific Neural Substrates for Bayesian-like Computations in Binocular Vision and Multisensory Processing, Vincent A. Billock, Leidos, Inc. at the Naval Aerospace Medical Research Laboratory, Naval Medical Research Unit - Dayton

  • Preclinical & clinical evaluation of flavoprotein fluorescence as a label-free biomarker of retinal mitochondrial stress, Tiffany Heaster, Genentech

  • Characteristics of electrically-induced visual percepts in the first human with the Intracortical Visual Prosthesis, Michael P Barry, Illinois Institute of Technology

11:50-12:00 Concluding Remarks